Mexican Chicken Casserole is a hearty and comforting dish packed with flavors like tender shredded chicken, melted cheese, beans, and a touch of zesty seasoning. With layers of tortillas or rice mixed in, it’s an easy, all-in-one meal that feels like a warm hug on a plate.
I love making this casserole when I want something simple to prepare but guaranteed to please everyone at the table. It’s one of those dishes you can easily customize with your favorite toppings like sour cream, avocado, or a little salsa. I also like to make extra so there’s plenty of leftovers to enjoy the next day.
Serving this casserole with a fresh green salad or some crunchy tortilla chips makes it even better. It’s the kind of meal that brings people together, perfect for family dinners or casual get-togethers. I always find that the cheesy, slightly spicy layers make everyone come back for seconds.
Key Ingredients & Substitutions
Chicken: Shredded cooked chicken breast works great here. You can swap this for rotisserie chicken to save time, or use shredded turkey for a twist. If you want it vegetarian, try substituting with cooked shredded jackfruit or extra beans.
Rice: White rice is easy and fluffy in this casserole, but brown rice adds a nuttier flavor and more fiber. For a low-carb version, use cauliflower rice instead. Just be sure to cook it first so the casserole isn’t watery.
Cheese: Cheddar and Monterey Jack melt beautifully and add creaminess. You can try pepper jack for mild spice or a Mexican cheese blend. For dairy-free options, use vegan cheese shreds, though the flavor may be milder.
Salsa: Salsa adds moisture and flavor. Use mild if you prefer less heat, or medium/hot for a spicier kick. If you don’t have salsa, try canned diced tomatoes with green chilies, or a tomato-based enchilada sauce.
Beans: Black beans are traditional and add protein and texture. Pinto beans make a good substitute. For an extra protein boost, you could add corn or cooked quinoa along with the beans.
How Can I Make Sure the Casserole Isn’t Too Wet or Dry?
Balancing moisture in this casserole is key to a great texture. Here are some tips:
- Drain and rinse canned beans well to avoid excess liquid.
- Cook rice just right—fluffy but not mushy.
- Mix salsa and sour cream thoroughly to spread moisture evenly.
- Don’t overdo extra sauces; you can always add more when serving.
- Let the casserole rest for 5 minutes after baking; this helps it set and makes it easier to serve.
Following these steps helps keep the casserole creamy without becoming soggy or dry. If you like a firmer casserole, bake uncovered as recommended to allow some moisture to evaporate.

Equipment You’ll Need
- 9×13 inch baking dish – great size for layering and baking your casserole evenly.
- Large mixing bowl – makes it easy to combine all the ingredients without spilling.
- Skillet or frying pan – to sauté onions and garlic for extra flavor.
- Measuring cups and spoons – to get your spices and ingredients just right.
- Wooden spoon or spatula – perfect for mixing without scratching your bowls or pans.
Flavor Variations & Add-Ins
- Swap chicken for cooked ground beef or turkey for a different protein texture and flavor.
- Add corn kernels or diced bell peppers for more crunch and color.
- Use pepper jack cheese instead of cheddar for a little extra spice.
- Include chopped jalapeños or a dash of hot sauce if you like more heat in your casserole.
How to Make Mexican Chicken Casserole
Ingredients You’ll Need:
Main Ingredients:
- 3 cups cooked, shredded chicken breast
- 1 1/2 cups cooked white rice
- 1 cup canned black beans, drained and rinsed
- 1 cup salsa (mild or medium heat, as preferred)
- 1/2 cup sour cream
- 1 small onion, finely chopped
- 2 cloves garlic, minced
- 1 tbsp olive oil
Spices & Cheese:
- 1 tsp ground cumin
- 1 tsp chili powder
- 1/2 tsp paprika
- 1/2 tsp salt
- 1/4 tsp black pepper
- 1 cup shredded cheddar cheese
- 1 cup shredded Monterey Jack cheese
Garnish:
- Fresh cilantro, chopped
- 1 small tomato, diced
- Optional: chopped green chiles or jalapeños for extra heat
How Much Time Will You Need?
This recipe takes about 15 minutes to prepare, including cooking onions and mixing ingredients, plus 20-25 minutes to bake. Allow an extra 5 minutes to let the casserole cool slightly before serving. In total, plan for about 40-45 minutes from start to finish.
Step-by-Step Instructions:
1. Prepare the Oven and Vegetables:
Preheat your oven to 375°F (190°C). Lightly grease a 9×13 inch baking dish to prevent sticking. Heat olive oil in a skillet over medium heat. Add finely chopped onion and minced garlic, and sauté until they are softened and fragrant—about 3 to 4 minutes.
2. Mix the Main Ingredients:
In a large mixing bowl, combine shredded chicken, cooked white rice, black beans, the sautéed onions and garlic, salsa, and sour cream. Sprinkle in ground cumin, chili powder, paprika, salt, and black pepper. Stir everything well to blend all the flavors together.
3. Add Cheese and Assemble:
Mix half of the shredded cheddar and Monterey Jack cheeses into the chicken mixture. Transfer this mixture evenly into the greased baking dish. Then sprinkle the remaining cheese evenly on top.
4. Bake and Serve:
Bake the casserole uncovered in the preheated oven for 20-25 minutes until it is bubbly and the cheese on top has melted and turned slightly golden. When ready, remove it from the oven and let it cool for about 5 minutes. Finish by garnishing with chopped cilantro and diced tomato. Serve warm with your favorite sides like sour cream, guacamole, or extra salsa for dipping.
Can I Use Frozen Chicken for This Casserole?
Yes, you can! Just make sure the chicken is fully thawed before shredding. Thaw it overnight in the fridge or use the defrost setting on your microwave for faster results.
Can I Make This Mexican Chicken Casserole Ahead of Time?
Absolutely! Prepare the casserole up to the baking step, cover it tightly, and refrigerate for up to 24 hours. When ready, bake it as directed, adding a few extra minutes if baking straight from the fridge.
How Should I Store Leftovers?
Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the microwave or oven until warmed through. Adding a splash of salsa or sour cream can help refresh the flavors.
Can I Substitute the Rice?
Yes! Brown rice or cauliflower rice work well as alternatives. Just ensure they’re cooked before adding to the casserole to avoid excess moisture or undercooked grains.



